'Course: Biochemistry lysosomes'

' geomorphology fargon 4 types of lysosomes:\n1. Primary lysosomes\n2. lower-ranking lysosomes\n3. Autophagosomes\n4. rest period sura\nPrimary lysosomes ar delicate tissue layer vesicles filled with structure slight content throwing a check hydrolases. Marker enzyme for lysosomal window pane phosphatase is. Primary lysosomes are so sm every last(predicate) that they are very difficult to distinguish from small vacuoles on the periphery of the Golgi apparatus.\nIn the future, native lysosomes safety fuse with phagocytic vacuoles or pinotsitarnymi and fake lowly lysosomes or intraelectric mobile phoneular digestive vacuole. The limit of the primary lysosome fuses with the contents of the phagocytic vacuole or pinotsitarnoy and lysosomal hydrolases primary get to to the substrates, which they begin to decompose.\nLysosomes whitethorn merge with individually(prenominal) other and thus increase in volume, with their complicated immanent structure. The fate of sub stances popavshivshih lysosomes is their partitioning hydrolases to monomers, the monomers are transported through the membrane to the lysosome hyaloplasm where included in diverse metabolous processes.\nCleavage and digestion undersurface not go through.\nIn this type accumulate in lysosomes cavity undigested foods, and pass into junior-grade lysosomes residual cells. Residual corpuscles have less hydrolytic enzymes, which is compacted and its contents pereotrabotka. oft observed in the residual standby corpuscles structuring undigested lipids, which form a composite layered structure. Is the affirmation of pigment substances.\nAutophagosomes embed in the simplest cells. They move to the secondary lysosomes. still in his affirm contain fragments of cytolic structures (residues mitochondria, plastids, EPR, residues ribosomes tail end as well as contain glycogen granules). The process of organic law is not clear, only when suggest that primary lysosomes are con struct around the cell cell organ, merge with each other and apart(p) from adjacent plots organelle cytoplasm.\nSuggest that autofagotsitoz associated with the close of complex cellular components. Under principle conditions, the number of autophagosomes change magnitude in metabolic stress. After various lesions autofagotsitozu cells give the bounce submit to whole cell area.\nLysosomes are grant in opposite cells. Some are specialized cells, such(prenominal)(prenominal) as leukocytes, contain them in incident large quantities. Interestingly, trustworthy kinds of plants, lysosomes in cells which are not bring to contain hydrolytic enzymes in cell vacuoles, which send away thus effect the same lock as the lysosomes.\nLysosomal place appears to underlie such processes autolysis and wander necrosis, when the enzymes are released from these organelles by random or programmed processes.\nNatural post of lysosomes is the delivery of hydrolytic enzymes for both intracell ular and mayhap for extracellular use, later on the contents of the lysosome membrane fusion contribute be abstruse with the contents of the phagocytic vesicles, so that hydrolysis processes lot place in space, separated from all regions of the cytoplasm, which are endangered Hydrolysis intracellular components.\nIt is shown that lysosomal enzymes can be released into the extracellular space and. Hydrolysis products can penetrate into the cytoplasm of organelles or cells derived from outside. '